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When you need to get away from it all, there’s nothing like total immersion in nature. From a serene retreat in Morocco’s Atlas Mountains, to a tropical oasis on Mexico’s Pacific Coast, these are the 16 most incredible new nature resorts in the world.

SB Winemaker’s House & Spa Suites — Mendoza, Argentina

Susana Balbo made history as Argentina’s first female winemaker. Now, the trailblazing vintner and her daughter, Ana, have opened Mendoza’s newest boutique hotel, set within their family’s former home in the leafy suburb of Chacras de Coria. The intimate hideaway fans outward from the Spanish-style bungalow — all arched doorways and beamed ceilings, with artwork culled from Balbo’s private collection — and encompasses seven “spa suites” with steam rooms, saunas, and sliding glass doors that open to private gardens. Wellness butlers are on hand to set up complimentary welcome massages and draw baths in the suite’s deep-soaking stone tubs, whose oval shapes are inspired by the concrete fermentation vats in Balbo’s winery, a half-hour from the hotel.

There, guests enjoy complimentary tours of the cellars and multi-course lunches with views of the Andes. Guests can also opt for an aerial safari in Balbo’s private seaplane which can whisk visitors to remote destinations not accessible to commercial carriers, such as the red rocks and arid desert of Cafayate or the secluded Lago La Plata in Argentina’s Patagonia. But most will be tempted to stay back at the hotel, lounging by the pool and enjoying long, leisurely lunches and traditional parrilla dinners at La VidA restaurant. And don’t sleep on the cocktails: mixologist Flavia Arroyo of Buenos Aires hotspot Casa Cavia has crafted an expertly curated drinks list, with options that incorporate Balbo’s award-winning torrontés and Provencal-style rosé. susanabalbohotels.com; doubles from $735. —Siobhan Reid.